BDBM103727 US10112907, Example 00033::US10206907, Compound 200::US10708263, Compound 1::US10766894, Compound TABLE 1.18::US10919890, Compound 1::US10961228, Example Filgotinib::US11000528, Cpd # 1::US11203595, TABLE 1.18::US11279699, Compound Filgotinib::US8563545, 1
SMILES O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1
InChI Key InChIKey=RIJLVEAXPNLDTC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 103727
Affinity DataIC50: 149nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 187nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 189nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+3nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) is purchased from Invitrogen. 0.025 mU of JAK3 is incubated wit...More data for this Ligand-Target Pair
Affinity DataIC50: 623nMAssay Description:Inhibition of JAK3 (unknown origin) in presence of ATP at Km concentration by caliper assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of JAK3 (unknown origin) expressed in mouse BAF3 cells assessed as antiproliferative activity by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 932nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr followed by anti-pSTAT1 antibody addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human JAK3 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 644nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of recombinant human JAK3 using GGEEEEYFELVKKKK as substrate incubated for 40 mins in presence of Mg/ATP mixture by [gamma p33]-ATP based ...More data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) in the presence of ATPMore data for this Ligand-Target Pair